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1

Evaluation of a high-content screening fluorescence-based assay analyzing the pharmacological modulation of lipid homeostasis in human macrophages

Tobias Werner, Gerhard Liebisch, Margot Grandl, Gerd Schmitz

Journal:

Cytometry Part A

Year:

2006

Language:

english

File:

PDF, 163 KB

english, 2006

2

E-LDL and Ox-LDL differentially regulate ceramide and cholesterol raft microdomains in human Macrophages

Margot Grandl, Salim Maa Bared, Gerhard Liebisch, Tobias Werner, Stefan Barlage, Gerd Schmitz

Journal:

Cytometry Part A

Year:

2006

Language:

english

File:

PDF, 107 KB

english, 2006

3

Fluorescent high-content imaging allows the discrimination and quantitation of E-LDL-induced lipid droplets and Ox-LDL-generated phospholipidosis in human macrophages

Margot Grandl, Gerd Schmitz

Journal:

Cytometry Part A

Year:

2010

Language:

english

File:

PDF, 711 KB

english, 2010

4

Oxidized LDL promotes, similar to the cationic amphiphiles and NPC1-mimetic U-18666A, endolysosomal phospholipidosis with extension of cell surface ceramide rafts

Gerd Schmitz, Margot Grandl

Journal:

Chemistry and Physics of Lipids

Year:

2007

Language:

english

File:

PDF, 60 KB

english, 2007

5

Ox-LDL induces endolysosomal phospholipidosis and ceramide species while E-LDL induces lipid droplets and cholesterylester in human macrophages

Margot Grandl, Gerhard Liebisch, Horst Robenek, Katharina Rübsamen, Alfred Boettcher, Marion Englmaier, Gerd Schmitz

Journal:

Chemistry and Physics of Lipids

Year:

2010

Language:

english

File:

PDF, 51 KB

english, 2010

6

Oxidized LDL-induced endolysosomal phospholipidosis and enzymatically modified LDL-induced foam cell formation determine specific lipid species modulation in human macrophages

Evelyn Orsó, Margot Grandl, Gerd Schmitz

Journal:

Chemistry and Physics of Lipids

Year:

2011

Language:

english

File:

PDF, 426 KB

english, 2011

7

SREBP-1c mediated induction of lipid metabolism is crucial for phagocytic differentiation of monocytes

Josef Ecker, Gerhard Liebisch, Marion Englmaier, Margot Grandl, Gerd Schmitz

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 205 KB

english, 2009

8

Ox-LDL and E-LDL loaded human macrophages show differential accumulation of atherogenic lipid classes and molecular species

Margot Grandl, Gerhard Liebisch, Katharina Ruebsaamen, Gerd Schmitz

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 53 KB

english, 2009

9

Induction of fatty acid and phospholipid synthesis is a key requirement for phagocytic differentiation of human monocytes

Josef Ecker, Gerhard Liebisch, Marion Englmaier, Margot Grandl, Horst Robenek, Gerd Schmitz

Journal:

Chemistry and Physics of Lipids

Year:

2010

Language:

english

File:

PDF, 57 KB

english, 2010

10

Differential regulation of fatty acid and plasmalogen species during monocyte–macrophage differentiation

Stefan Wallner, Josef Ecker, Margot Grandl, Markus Peer, Gerhard Liebisch, Gerd Schmitz

Journal:

Chemistry and Physics of Lipids

Year:

2011

Language:

english

File:

PDF, 42 KB

english, 2011

11

Crosstalk between apoA-I/ABCA1 and apoE ceramide pathway in Ox-LDL and E-LDL loaded human macrophages

Katharina Leidl, Margot Grandl, Gerhard Liebisch, Alfred Böttcher, Gerd Schmitz

Journal:

Chemistry and Physics of Lipids

Year:

2007

Language:

english

File:

PDF, 47 KB

english, 2007

12

Ox-LDL provokes phospholipidosis and ceramide membrane microdomain formation in human macrophages

Margot Grandl, Gerhard Liebisch, Horst Robenek, Katharina Leidl, Alfred Boettcher, Marion Englmaier, Sascha Bandulik, Tobias Werner, Andrzej Sobota, Gerd Schmitz

Journal:

Chemistry and Physics of Lipids

Year:

2008

Language:

english

File:

PDF, 54 KB

english, 2008

13

Highly efficient and low-cost method to isolate human blood monocytes with high purity

Fabian Stögbauer, Markus Neumeier, Johanna Weigert, Josef Wanninger, Margot Grandl, Karla Lehle, Gerd Schmitz, Charalampos Aslanidis, Andreas Schäffler, Jürgen Schölmerich, Christa Buechler

Journal:

Journal of Immunological Methods

Year:

2008

Language:

english

File:

PDF, 265 KB

english, 2008

14

Analyzing M-CSF dependent monocyte/macrophage differentiation: Expression modes and meta-modes derived from an independent component analysis

Dominik Lutter, Peter Ugocsai, Margot Grandl, Evelyn Orso, Fabian Theis, Elmar W Lang, Gerd Schmitz

Journal:

BMC Bioinformatics

Year:

2008

Language:

english

File:

PDF, 560 KB

english, 2008

15

Gene expression profiling identifies retinoids as potent inducers of macrophage lipid efflux

Thomas Langmann, Gerhard Liebisch, Christoph Moehle, Rainer Schifferer, Rania Dayoub, Susanne Heiduczek, Margot Grandl, Ashraf Dada, Gerd Schmitz

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2005

Language:

english

File:

PDF, 265 KB

english, 2005

16

β-Amyloid (Aβ40, Aβ42) binding to modified LDL accelerates macrophage foam cell formation

Berta Schulz, Gerhard Liebisch, Margot Grandl, Tobias Werner, Stefan Barlage, Gerd Schmitz

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2007

Language:

english

File:

PDF, 604 KB

english, 2007

17

Endolysosomal phospholipidosis and cytosolic lipid droplet storage and release in macrophages

Gerd Schmitz, Margot Grandl

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2009

Language:

english

File:

PDF, 685 KB

english, 2009

18

E-LDL upregulates TOSO expression and enhances the survival of human macrophages

Alexander Sigruener, Christa Buechler, Salim Maa Bared, Margot Grandl, Charalampos Aslanidis, Peter Ugocsai, Mathias Gehrmann, Gerd Schmitz

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 368 KB

english, 2007

19

Lower SCD expression in dendritic cells compared to macrophages leads to membrane lipids with less mono-unsaturated fatty acids

Josef Ecker, Gerhard Liebisch, Margot Grandl, Gerd Schmitz

Journal:

Year:

2010

Language:

english

File:

PDF, 788 KB

english, 2010

20

Expression pattern and raft association of NIPSNAP3 and NIPSNAP4, highly homologous proteins encoded by genes in close proximity to the ATP-binding cassette transporter A1

Christa Buechler, Marek Bodzioch, Salim Maa Bared, Alexander Sigruener, Alfred Boettcher, Katarzyna Lapicka-Bodzioch, Charalampos Aslanidis, Chinh Quoc Duong, Margot Grandl, Thomas Langmann, Aldona De

Journal:

Year:

2004

Language:

english

File:

PDF, 614 KB

english, 2004

21

Role of Redox Regulation and Lipid Rafts in Macrophages During Ox-LDL–Mediated Foam Cell Formation

Schmitz, Gerd, Grandl, Margot

Journal:

Antioxidants & Redox Signaling

Year:

2007

Language:

english

File:

PDF, 1.56 MB

english, 2007

22

Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes

Josef Ecker, Gerhard Liebisch, Marion Englmaier, Margot Grandl, Horst Robenek, Gerd Schmitz and David W. Russell

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.58 MB

english, 2010

23

Human native, enzymatically modified and oxidized low density lipoproteins show different lipidomic pattern

Orsó, Evelyn, Matysik, Silke, Grandl, Margot, Liebisch, Gerhard, Schmitz, Gerd

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2015

Language:

english

File:

PDF, 935 KB

english, 2015

24

Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes

Ecker, Josef, Liebisch, Gerhard, Englmaier, Marion, Grandl, Margot, Robenek, Horst, Schmitz, Gerd

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 839 KB

english, 2010

25

Update on lipid membrane microdomains

Schmitz, Gerd, Grandl, Margot

Journal:

Current Opinion in Clinical Nutrition & Metabolic Care

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

26

Monocyte to Macrophage Differentiation Goes along with Modulation of the Plasmalogen Pattern through Transcriptional Regulation

Wallner, Stefan, Grandl, Margot, Konovalova, Tatiana, Sigrüner, Alexander, Kopf, Thomas, Peer, Markus, Orsó, Evelyn, Liebisch, Gerhard, Schmitz, Gerd, Langmann, Thomas

Journal:

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

27

oxLDL and eLDL Induced Membrane Microdomains in Human Macrophages

Wallner, Stefan, Grandl, Margot, Liebisch, Gerhard, Peer, Markus, Orsó, Evelyn, Sigrüner, Alexander, Sobota, Andrzej, Schmitz, Gerd, Cowart, Ashley

Journal:

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

28

Phosphatidylcholine and phosphatidylethanolamine plasmalogens in lipid loaded human macrophages

Wallner, Stefan, Orsó, Evelyn, Grandl, Margot, Konovalova, Tatiana, Liebisch, Gerhard, Schmitz, Gerd, Cignarella, Andrea

Journal:

Year:

2018

Language:

english

File:

PDF, 5.85 MB

english, 2018

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